Causes of Mesothelioma – Malignant Mesothelioma Information #causes #of #mesothelioma, #malignant #mesothelioma #asbestos #asbestosis #cancer


Causes of Mesothelioma

Asbestos exposure is one of the most common causes of mesothelioma. Over 50 percent of mesothelioma patients have a history of asbestos exposure. This exposure could occur while directly handling the fibrous material, or it could occur through just environmental exposure.

There are numerous documented cases where patients contracted the disease due to living close to the asbestos mines or by coming in contact with asbestos when some of the fibers became airborne. Persons most commonly afflicted include shipyard workers, construction workers, automobile mechanics (particularly those working on brake linings), insulation workers, pipe and heater installation and flooring workers and roofers.

Also, for those who have had asbestos exposure and who smoke, the risk becomes exaggerated. Studies show that asbestos workers who also smoke are 55 times more likely to die of mesothelioma than nonsmokers without asbestos exposure.

Erionite

Erionite is a mineral that has a long, thin rod-like amphiboles structure. Exposure to this mineral has been associated with increased incidence of mesothelioma. Many cases of mesothelioma due to erionite exposure have been diagnosed in the Central Anatolia region of Turkey.

Exposure to asbestos is the primary cause for malignant mesothelioma in most patients. If you or a loved one has been exposed to asbestos, then you are at risk. There is no minimum level of exposure that is deemed safe. Insure that during your routine health care, you advise your doctor of previous asbestos exposure, particularly if you experience any chest pressure, shortness of breath, chest pain or coughing. While these symptoms do not indicate the presence of the disease, they are the most common symptoms and should be further investigated if you have had asbestos exposure.

[Page updated February 2005]

Serving Clients Throughout California
Call Today

ATTORNEY ADVERTISEMENT Thank you for your visit. This website was created to provide persons affected by mesothelioma with current, up-to-date information. The content published on this website was not written by medical professionals and should not, at any point, be mistaken for medical advice. Furthermore, the information on this site is intended for educational purposes only and should never interfere with a patient/site visitor and his or her healthcare provider. In addition, viewing the content on this website, requesting additional information, or transmitting information through a contact form should never be considered the formation of an attorney-client relationship. The material published on this site is general and may not apply to your specific circumstances. Every case comes with its own set of unique circumstances; past success discussed on this site does not guarantee future performance. Information found on this website should not be used as incentive to act without seeking counsel from a professional.

All About Malignant Mesothelioma: Your Mesothelioma Information Source
2005-2015 Ceatus Media Group LLC
Copying or reproducing any text or graphics from this website is strictly prohibited by copyright law.


Statistics – Asbestos related lung cancer #statistics, #statistical, #data, #diseases, #asbestos, #asbestosis, #lung #cancer, #tobacco #smoke, #exposure, #mesothelioma, #deaths, #


#

Asbestos related lung cancer

Summary

  • The overall scale of asbestos-related lung cancer deaths has to be estimated rather than counted.
  • Research suggests there are currently about as many lung cancer deaths attributed to past asbestos exposure each year in Great Britain as there are mesothelioma deaths.
  • This implies there are currently in excess of 2,000 asbestos-related lung cancer deaths each year.
  • This estimate is uncertain, and since asbestos and smoking act together to increase the risk, it is affected by past smoking habits as well as asbestos exposure.

Background information

Asbestos is one of a large number of agents that can cause lung cancer, the most important of which is tobacco smoking.

Lung cancer usually has no specific clinical signs suggesting a particular cause and asbestos exposure and smoking act together to increase the risk. This – together with the fact that cases usually take many years to develop – makes it difficult to be sure about the cause of individual cases. As a consequence, data sources that rely on the counting of individual cases attributed to asbestos exposures, such as Industrial Injuries Disablement Benefit (IIDB) and the Health and Occupation Reporting (THOR) schemes, tend to underestimate the true scale of asbestos-related cases.

Epidemiological analyses that are representative of the British population suggest that there are likely to be about as many lung cancer cases attributed to past asbestos exposure each year in the population as a whole as there are mesotheliomas 1. 2. This implies there are currently in excess of 2000 asbestos-related lung cancer deaths each year.

This estimate is uncertain. Since asbestos and smoking act together to increase the risk of lung cancer, it is affected by past smoking habits as well as the extent of asbestos exposure. The ratio of lung cancers to mesotheliomas is expected to fall over time, a reflection of reductions in both asbestos exposure and the prevalence of smoking. Among more specific groups of workers heavily exposed to asbestos in the past there were typically a greater number of excess lung cancer cases than there were mesotheliomas 3.

Lung cancer is still typically fatal within a few years of diagnosis and so, as with the mesothelioma, the number of annual deaths is similar to the annual incidence of new cases.

In recent years there have been, on average, around 300 new cases of asbestos-related lung cancer each year within the IIDB scheme and less than 100 cases identified by chest physicians each year within the THOR scheme.

Estimates of the burden of lung cancer attributable to occupational exposures other than asbestos are available based on the Burden of Occupational Cancer research.

References

  1. Darnton A, McElvenny D, Hodgson J (2005). Estimating the number of asbestos related lung cancer deaths in Great Britain from 1980-2000. Annals of Occupational Hygiene 50(1): 29-38.
  2. Gilham C, Rake C, Burdett G et al (2015). Pleural mesothelioma and lung cancer risks in relation to occupational history and asbestos lung burden. Occup Environ Med. 73(5):290-9.
  3. McCormack V, Peto J, Byrnes G et al (2012). Estimating the asbestos-related lung cancer burden from mesothelioma mortality. Br J Cancer. 106(3):575-84.

Resources


Lung-Sparing Surgery May Up Mesothelioma Survival #mesothelioma, #mesothelioma #treatment, #surgery, #lung, #lung #cancer, #mesothelioma #surgery, #asbestos


#

Lung-Sparing Surgery May Up Mesothelioma Survival

By Maureen Salamon

FRIDAY, Dec. 23, 2016 (HealthDay News) — Surgery that preserves the lung. when combined with other therapies, appears to extend the lives of people with a subtype of the rare and deadly cancer mesothelioma. a new study suggests.

Tracking 73 patients with advanced malignant pleural mesothelioma — which affects the lungs’ protective lining in the chest cavity — researchers found that those treated with lung-sparing surgery had an average survival of nearly three years. A subset of those patients survived longer than seven years.

Mesothelioma patients treated with chemotherapy alone, which is standard care, live an average of 12 to 18 months, the researchers said.

Study participants received lung-sparing surgeries and another treatment called photodynamic therapy that uses light to kill cancer cells. Ninety-two percent of the group also received chemotherapy.

The study volunteers achieved far longer survival times, said study author Dr. Joseph Friedberg.

“When you take the [entire] lung out, it’s a significant compromise in quality of life,” said Friedberg. He’s director of the University of Maryland Medical Center’s Mesothelioma and Thoracic Oncology Treatment and Research Center in Baltimore.

“For all intents and purposes, this [lung-sparing surgical approach] is the largest palliative operation known to man, since chances of curing mesothelioma are vanishingly small,” said Friedberg. He completed the research while at his previous post at the University of Pennsylvania.

“Plus, most of these patients are elderly, so preserving quality of life was really the goal,” he added.

About 3,000 Americans are diagnosed with mesothelioma each year, the American Cancer Society says. Many of these people were exposed to the mineral asbestos in industrial occupations, according to the U.S. National Cancer Institute (NCI).

Used in products such as insulation, building shingles and flooring, asbestos dust fibers can be inhaled or swallowed, settling in the lungs, stomach or other body areas. Often, it takes decades after exposure for mesothelioma to develop, the NCI says.

Friedberg and his team performed the lung-sparing surgeries on study participants between 2005 and 2013. Overall average survival was 35 months, the study showed. But survival time more than doubled to 7.3 years for 19 patients whose cancer had not spread to their lymph nodes.

Continued

Most of the patients in the study had stage 3 or stage 4 cancer. Typically, Friedberg said, only about 15 to 20 percent of mesothelioma patients are treated with surgery, which often removes an entire lung as well as the diaphragm and the sac surrounding the heart .

Friedberg said that between 20 and 40 percent of pleural mesothelioma patients with the epithelial subtype might be eligible for lung-sparing surgery. He explained that this surgery removes all visible traces of cancer. It typically has fewer complications and a lower risk of dying in the 90 days following the 10- to 14-hour procedure.

“It’s still relatively new that people do lung-sparing surgery for this disease, and it’s not established that this is what we need to do,” said Friedberg.

“I would say this is one of the most lethal cancers known to man. There’s a pressing need for new and innovative treatments,” he noted.

Another mesothelioma expert said he was cautiously optimistic about the new study’s results.

“It’s not a randomized trial and I think they selected out. only those patients who were well enough to get to surgery and those with the epithelial subtype who are the patients who tend to do the best,” said Dr. Gregory Masters.

He is principal investigator with the U.S. National Cancer Institute Community Oncology Research Program at the Helen F. Graham Cancer Center and Research Institute in Newark, Del.

“Taking the best patients is going to skew the study and make the outcome look very good,” added Masters. “But I am encouraged they can take a large group of patients and show such a good outcome at three years.”

Dr. Daniel Petro, a medical oncologist/hematologist at the University of Pittsburgh Medical Center, said lung-sparing surgery for mesothelioma is also done at academic centers such as his, and he was not surprised by the study’s results.

“This [surgical approach] is a step forward with this particular terrible cancer,” Petro said, “and we’ve got to keep coming up with better options to eradicate it.”

The study was published in the December issue of Annals of Thoracic Surgery.

WebMD News from HealthDay

Sources

SOURCES: Joseph S. Friedberg, M.D. director, Mesothelioma and Thoracic Oncology Treatment and Research Center, University of Maryland Medical Center, and professor, surgery, and head, Division of Thoracic Surgery, University of Maryland School of Medicine, Baltimore; Gregory A. Masters, M.D. principal investigator, U.S. National Cancer Institute Community Oncology Research Program (NCORP), Helen F. Graham Cancer Center and Research Institute, Christiana Care Health System, Newark, Del.; Daniel Petro, M.D. medical oncologist/hematologist, Hillman Cancer Center, University of Pittsburgh Medical Center; December 2016, Annals of Thoracic Surgery

Top Picks


Wisconsin Mesothelioma Attorney #wisconsin, #mesothelioma, #asbestos, #attorney, #what #is #asbestos, #what #is #mesothelioma, #asbestos #attorneys, #mesothelioma #attorneys


Wisconsin Mesothelioma Attorney

If you are a victim of mesothelioma, and you have been exposed to asbestos at your job site, you should contact a Wisconsin mesothelioma attorney and file a case against the companies that exposed you to asbestos. Mesothelioma is a deadly condition and your Wisconsin mesothelioma lawyer can help you claim retribution for your suffering. Many people have lost since there are no active mines of asbestos [1] in Wisconsin where asbestos occurs naturally, all forms of asbestos exposure and the diseases associated with it originate from work related and industrial exposures to asbestos in Wisconsin. The only natural deposits in the entire state are found along Wisconsin’s border connecting it with the upper peninsula of Michigan. Paper mills, chemical and power plants and construction companies are mainly responsible for the contamination of asbestos in Wisconsin. It is also a fact that the total paper production that takes place in Wisconsin alone is greater than that which is done in most other states.

If you live near or worked at any of the asbestos contaminated job sites mentioned below, it is important for you to get a mesothelioma screening done as soon as possible. Asbestos is the only known cause of mesothelioma, which is a fatal condition. Mesothelioma takes decades to develop, and usually when it is diagnosed, it is in its latest and most dangerous stages, making treatment difficult.

Sites that increase the risk of asbestos exposure:

If you have worked at any of the below mentioned job sites, and suffer from mesothelioma, you should contact a Wisconsin mesothelioma lawyer and seek retribution for the pain and the suffering you are going through.

Paper mills: paper production companies use asbestos liberally for the purposes of insulation. Decades ago, asbestos related products as well as asbestos itself were used as components of the pulp in the form of adhesives and drying felts. It is important to change these drying felts every now and then which automatically enhances and increases the chances of asbestos exposure caused to the workers. The greatest sources of asbestos exposure in Wisconsin, as well as many other states in America are paper and pulp manufacturing industries.

Chemical and Power plants. chemical plants and power plants also use asbestos for the purposes of insulation as it has an excellent ability to absorb heat.

Construction companies. construction materials used in industrial and public buildings included asbestos before the 1970’s and 80’s, when this substance was finally banned because of its health hazards. Buildings that were constructed before these decades were made using asbestos as part of the construction material and included some or all of the following mentioned substances: concrete wallboard combined with asbestos, a spray used for insulation purposes also containing asbestos, ceiling and floor tiling with asbestos containing materials, countertops made with asbestos, paints containing asbestos fibers for heat and chemical insulation purposes.

Power generation plants: The forms of asbestos which are significantly resistant to heat energy are amphiobole asbestos. Amphiobole minerals [2] are highly toxic as well as heat resistant. Before their toxicity was known about, they were readily used in the construction of many power generation plants and units throughout the state, as well as all over the country.

Electrical machinery: Asbestos containing materials can also be found in the electrical machinery and units, electrical cloths and also conduits. These include major generators and turbines that are used for the production of electricity. Asbestos used in the manufacture of these machineries and electrical units is extremely dangerous because it allows for the release of minute and fine fibers of asbestos into the environment which can then be easily inhaled or ingested by people, causing them to fall victims to the dangerous diseases and disorders that asbestos exposure can cause.

According to a survey done in the year 2003, conducted in Puerto Rico, the chest x rays of a huge number of workers were examined. One hundred and thirty of these x rays led to the diagnosis of diseases caused by asbestos exposure. It is for this reason that it is important for all workers that have been employed at any of these industrial sites, or even people who reside in the same area as any of these plants that have confirmed asbestos exposure must immediately consult specialized mesothelioma clinics which have been established in the state in order to provide treatment and medication to those who have fallen victims to the hazards of asbestos exposure and the diseases caused by it.

Mesothelioma and asbestos:

Asbestos exposure can induce the development of a rare lung cancer known as mesothelioma, which is fatal to humans. Another disease caused by asbestos exposure is asbestosis, also known as pleural mesothelioma, which is not fatal but harmful to those exposed to the mineral. In Wisconsin over 700 people have died of mesothelioma or asbestosis since the year 1979 though the year 2001. Lung cancers caused due to asbestos exposure are also very frequent. If you or a family member suffers from mesothelioma, you should contact a Wisconsin mesothelioma attorney to help you file your case.

Mesothelioma treatment centers in Wisconsin:

The following treatment center in the state of Wisconsin offer treatment for this deadly condition:

University of Wisconsin Carbone Cancer treatment center:

This center is located in Madison. The Paul P. Carbone Comprehensive Cancer Center [3] is a top of the line treatment center for those people in the Madison and its neighboring areas in Wisconsin who may be feelings the symptoms of asbestos related conditions. The center should be contacted immediately if you have worked at any of the above mentioned job sites in the state of Wisconsin. Most workers who had been employed at these asbestos contaminated job sites were not aware of the risks of asbestos related diseases like mesothelioma, lung cancer and asbestosis.

UW PAUL P. CARBONE

COMPREHENSIVE CANCER CENTER

UNIVERSITY OF WISCONSIN

600 HIGHLAND AVENUE,

MADISON, WISCONSIN 53792-0001